Prevent Cancer News
cancersolutions
anticancer
preventcancer

Unique probiotic yeast can help prevent colorectal cancer, says study

07/27/2019 / By Ralph Flores


Pichia kudriavzevii, a probiotic yeast found in fermented dairy products and tea, potentially holds anti-cancer properties, according to researchers from Iran’s Tabriz University of Medical Science. The study, which appeared in the journal Nutrition Research, looked at the apoptotic effects of P. kudriavzevii As-12 supernatant – the residual liquid produced after centrifugation against different colorectal cancer cells – as well as the mechanism behind its anti-cancer activity.

For the study, the researchers tested whether the supernatant was toxic to colorectal cancer cells in vitro and found that those that were treated with metabolites from the P. kudriavzevii As-12 supernatant decreased significantly compared to control. The survival rates of the cancer cells after treatment were between 42.5 and 67.5 percent. In addition, the colorectal cancer cells also showed signs of shrinkage and death (apoptosis). The researchers observed that while the nuclei of the cancer cells were either condensed or fragmented – which indicated early or late apoptosis, respectively – this was not seen in normal cells that were exposed to the metabolites.

The ability of the metabolites to induce apoptosis was comparable to 5-FU (fluorouracil), a drug often used to treat colorectal cancer. Often used in chemotherapy, 5-FU was found to cause long-term brain damage, years after the treatment was completed. (Related: Cancer Drug Causes Permanent Brain Damage.)

The anti-cancer activity shown by P. kudriavzevii could be used to develop a natural agent that specifically targets colorectal cancer cells to induce apoptosis, the researchers proffered. In general, commercial chemotherapeutic drugs target cells indiscriminately, often leading to toxic, immunosuppressive, mutagenic, and carcinogenic side effects.

This also adds another strain to the growing list of probiotic yeasts, based on in vivo and in vitro studies. Another probiotic yeast that showed similar anti-cancer activity is Saccharomyces boulardii, a strain often used for treating harmful Candida overgrowth in the gut. Kluyveromyces marxianus BO399, a lactic yeast, modulated immune response and decreased pro-inflammatory cytokines.

In addition to its anti-cancer activity, P. kudriavzevii also possesses multiple biological activities, all of which have been widely studied. It can strengthen the gut from infectious agents by neutralizing bacterial toxins, improving the immune response of the mucosa, and modulating the cell proliferation signaling pathway of the host to prevent inflammation.

“Pichia kudriavzevii AS-12 secretion metabolites possess anticancer activity against human colorectal cancer cell lines,” the researchers wrote in their study.

Probiotics: not just bacteria

Most people associate probiotics to bacteria, that’s why they are referred to as “good bacteria.” While probiotic bacteria are indeed beneficial to the body, it’s worth noting that there are certain types of yeast that have probiotic potential. In an article in Alimentary Pharmacology and Therapeutics, researchers investigated S. boulardii to determine properties that are unique to probiotic yeast.

One of the traits of probiotic yeast that the researchers found to be advantageous is its ability to tolerate extreme stress. Many types of yeast can better handle differing pH levels than bacteria, with some being unaffected by highly acidic environments. This makes them great at handling issues in the gastrointestinal (GI) tract.

The article found that S. boulardii, when mixed with Lactobascillus acidophilus and Bifidobacterium bifidum, showed significant efficacy against pathogens in traveler’s diarrhea. It was also found to be effective against acute diarrhea in children, which can lead to life-threatening cases of dehydration, after only four days.

AntiCancer.news has more on foods that help keep cancer at bay.

Sources include:

NaturalNews.com

ScienceDirect.com

WellAndGood.com

OnlineLibrary.Wiley.com

Tagged Under: anticancer, cancer cures, disease treatments, food cures, food is medicine, food science, functional food, natural cures, natural medicine, Pichia kudriavzevii AS-12, prevention, probiotic yeast, probiotics, research, yeast



Comments

RECENT NEWS & ARTICLES

Unique probiotic yeast can help prevent colorectal cancer, says study
07/27/2019 / By Ralph Flores
Forsythiae Fructus, a detoxifying herb used in TCM, found to have anti-tumor effects
07/24/2019 / By Michelle Simmons
What do eggs, pecans, and dairy products have in common? Hint: It has to do with your risk of heart disease and cancer
07/23/2019 / By Zoey Sky
Avoid “kid” food: Keeping your kids away from hot dogs and processed meat can reduce their risk of leukemia
07/14/2019 / By Tracey Watson
Provide the best possible environment for your genes: Eat more turmeric
07/14/2019 / By Isabelle Z.
Top 4 natural remedies for SKIN CANCER the FDA does NOT want you using: Part II
07/10/2019 / By S.D. Wells
Shockingly effective: Just ONE week of eating an organic diet removes pesticides from your body
07/10/2019 / By Lance D Johnson
B-type proanthocyanidins in Masson’s pine bark extract show antioxidant and antitumor properties
07/09/2019 / By Evangelyn Rodriguez
Extracts from Zanthoxylum armatum demonstrate cytotoxic activity on human breast and colorectal cancer cells
07/09/2019 / By Ralph Flores
6 Reasons to eat more onions
07/08/2019 / By Melissa Smith
Plums can prevent colon cancer cells from spreading – study
07/03/2019 / By Michelle Simmons
Astragalus membranaceus relieves inflammation and protects against gastrointestinal cancer: Review
07/03/2019 / By Janine Acero
Polysaccharides from medicinal herbs demonstrate antioxidant and anti-tumor properties
07/03/2019 / By Michelle Simmons
Chebulinic acid, a primary component in triphala, demonstrates anti-tumor properties
07/02/2019 / By Evangelyn Rodriguez
Black nightshade reduces growth of cancerous tumors
07/02/2019 / By Michelle Simmons
Formula made using TCM herbs exhibits anticancer effects against metastatic breast cancer
07/02/2019 / By Evangelyn Rodriguez
TCM’s red sage is lethal to drug-resistant cancer
07/02/2019 / By Michelle Simmons
Huge finding: Japanese knotweed can inhibit growth of (and destroy) liver cancer stem cells
06/28/2019 / By Evangelyn Rodriguez
Do you have this ancient, cancer-fighting medicine growing in your yard? Commonly considered a weed now, most people try to eradicate it
06/27/2019 / By Isabelle Z.
Calorie restriction is bad news for cancer cells: It makes them “eat themselves”
06/20/2019 / By Ralph Flores

COPYRIGHT © 2017 PREVENT CANCER NEWS

Privacy Policy